TROPHEN

Sterile Eye Drops

Description:

Trophen sterile Eye drops is a combination of Tropicamide and Phenylephrine Hydrochloride. Tropicamide is an anticholinergic which paralyses the sphincter muscle of the iris resulting in pupillary dilatation. The ciliary muscle is also paralyzed leading to loss of accommodation.

Phenylephrine Hydrochloride is a selective alpha-1 agonist, which causes mydriasis without cycloplegia .It tends to reduce intraocular lesion by vasoconstrictor action.

Composition:

Each ml contains Tropicamide USP 8 mg and Phenylephrine Hydrochloride USP 50 mg.

Indication:

As a mydriatic, Trophen is indicated in some pre & post-operative states and for ophthalmologic examinations like during ophthalmoscopy, slit-lump examination, retinal photography, laser treatment or adjunct in the treatment of anterior uveitis. It also may be used in temporary lowering of intraocular pressure in glaucoma.

Dosage and Administration:

Instill 1-2 drops in the eye(s)15-20 minutes before examination. If examination is not conducted within 20–30 minutes, an additional drop may be placed in the eye(s) to prolong the effect.

Contraindication:

Known hypersensitivity to any ingredient of the preparation, and narrow angle glaucoma.

Side effects:

Ocular side effects include transient stinging and raised intra-ocular pressure; on prolonged administration local irritation, hyperemia odema and conjunctivitis may occur. Systemic effects include arrhythmias, hypertension, and coronary artery spasm.

Drug interaction:

Phenylephrine may interact with systemically administered Monoamino Oxidase Inhibitors (MAOIs).

Precaution:

Children and elderly; cardiovascular diseases, tachycardia, hypertension, diabetes.

Storage condition:

• Keep out of the reach of children.

• Keep the container tightly closed and store below 250 C, away from direct sunlight.

• Do not refrigerate.

• Discard after one month after first opening the bottle.

Packing:

Plastic dropper bottle of 5ml eye drops.