Compostion:

ZnF tablet: Each film coated tablet contains Folic acid BP 5 mg and Zinc Sulfate Monohydrate USP 54.90 mg equivalent to elemental Zinc 20 mg.

Pharmacology:

Zinc is an essential element in human health with a wide range of roles. It plays as a coenzyme for more than 200 enzymes. These enzymes are involved in nucleic acid and protein metabolism and the production of energy. Zinc is vital for growth and development. Zinc deficiency can result in growth retardation, immune dysfunction, increased incidence of infections, anorexia, weight loss, neural tube defects of the foetus, increased risk for abortion and mental lethargy. Folic Acid is the member of B-vitamin group. Folic Acid participates in several key biological processes, including the synthesis of DNA, RNA and proteins. It is necessary for DNA replication and is involved in the regulation of gene expression. Folic Acid deficiency in pregnant women results in an increased incidence of neural tube defects, including meningomyelocele (e.g., spina bifida), anencephaly, meningocele and craniorachischisis, in their neonates. Folic Acid deficiency leads to megaloblastic anemia. Other symptoms and signs of Folic Acid deficiency include weakness, fatigue, irritability, headache, difficulty concentrating, palpitations etc.

Indication:

ZnF acid is indicated as the prophylaxis and in the treatment of Zinc and Folic Acid deficiencies.

Dosage and Administration:

One tablet daily or as recommended by the physician.

Side Effect:

This tablet is well tolerated. Sometimes gastrointestinal disturbances like abdominal pain, dyspepsia, nausea, vomiting, fever, and respiratory distress may occur.

Use in pregnancy and lactation:

Recommended.

Contraindication:

ZnF is contraindicated in patients having hypersensitivity to Zinc. Folic Acid is contraindicated in untreated cobalamine deficiency.

Drug Interaction:

Large amount of calcium decreases the absorption of Zinc. In case of Folic Acid, no drug interactions have been reported.

Overdosage:

Zinc Sulfate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach.

Storage condition:

Store in a cool & dry place, protected from light & moisture. Keep out of reach of children.

Packaging:

ZnF tablet: Box containing 5X10’s tablets in blister pack