CALBON D

Calcium+Vitmin D3

Description:

Calbon D is a combination of Calcium & Vitamin D3. Calcium is needed for the formation of strong bones and healthy teeth and is involved in helping the blood to clot. It is also required to transmit nerve signals and help muscles work. Vitamin D3 improves the absorption of calcium into the body.

Composition:

Each tablet contains Calcium carbonate USP 1250 mg equivalent to 500 mg of elemental calcium & vitamin D3 BP 200 IU as Cholecalciferol.

Indications:

Calcium & vitamin D is indicated in

• Treatment of osteoporosis, rickets, osteomalacia, tetany and parathyroid disease.
• In pregnancy & lactation due to increased demand
• In kidney disease and pancreatitis
• During therapy with anti-seizure medications.
• The prevention & treatment of calcium or vitamin D deficiency specially in the housebound and institutional elderly patients.

Dosage & Administration:

Adults and elderly and children above 12 years of age: 2 tablets per day, preferably one tablet morning and evening.

Contraindication:

Hypersensitivity to any component of the product. Hypercalcaemia for example, as a result of hyperparathyroidism, vitamin D overdose, decalcifying tumours scuh as myeloma, bone metastases or sarcoidosis. Severe hypercalciuria, renal stones. Osteoporosis due to immobilization.

Side-effects:

The use of calcium supplements has rarely given rise to mild gastro-intestinal disturbances, such as constipation, flatulence, nausea, gastric pain, diarrhoea. Following administration of vitamin D supplements occasional skin rash has been reported. Hypercalcuria, and in rare cases hypercalcaemia have been seen with long term treatment at high dosages.

Precaution:

Hypercalcaemia should particularly be avoided in digitalized patients. Patients with mild to moderate renal failure (commonly found in the elderly) mild hypercalcuria should be supervised carefully with periodic checks of urinary calcium excretion and plasma calcium levels.

Urinary calcium excretion should also be measured in patients with a history of renal stones to exclude hypercalcuria.

Use in Pregnancy & Lactation:

Normal requirements of calcium & vitamin D are raised during pregnancy & lactation. Calcium is excreted in breast milk but not sufficiently to produce adverse effect I the infant. Allowances should be made for vitamin D/calcium from other sources. During pregnancy & lactation therapy should be under medical supervision.

Children: children under 12 years of age should not take this preparation.

Drug Interactions:

The risk of hypercalcaemia should be considered in patients taking thiazide diuretics since these drugs can reduce urinary calcium excretion. Hypercalcaemia must be avoided in digitalized patients.

Certain foods (e.g. those containing oxalic acid, phosphate or phytinic) may reduce the absorption of calcium.

Concomitant treatment with phenytoin or barbiturates can decrease the effect of vitamin D because of metabolic activation.

Concomitant use of glucocorticoids can decrease the effect of vitamin D.

The effects of digitalis and other cardiac glycosides may be accentuated with the oral administration of calcium combined with vitamin D. strict medical supervision is needed and, if necessary monitoring of ECG and calcium.

Calcium salts may reduce the absorption of thyroxine, biphosphonates, sodium fluoride, quinolone or tetracycline antibiotics or iron. It is advisable to allow a minimum period of four hours before taking the calcium.

Overdose:

The most serious consequence of acute or chronic overdose is hypercalcaemia due to vitamin D toxicity. Symptoms include nausea, vomiting, polyuria and constipation. Chronic overdoses can lead to vascular and organ calcification as a result of hypercalcaemia.

Storage:

Store in a cool and dry place. Protect from light. Keep out of the reach of children. Keep the bottle tightly closed.

Packaging:

Bottle containing 15's & 30's tablet.