GLUCOMET

Metformin

Composition:

Glucomet-500 Tablet: Each tablet contains Metformin Hydrochloride BP 500 mg.

Glucomet-850 Tablet: Each tablet contains Metformin Hydrochloride BP 850 mg.

Indications:

• Non-insulin dependent adult diabetes mellitus, when over weight or obesity not responding to dietary therapy.

• Glucomet can be given alone as initial therapy or can be administered in combination with a sulfonylurea.

• In insulin dependent diabetics, Glucomet may be given as an adjuvant to patients whose symptoms are not well controlled and who are often obese.

Dosage & administration:

Glucomet should be taken in divided doses with meals. The initial dose is 500 mg three times daily or the mean daily dose is 850 mg in the morning and in the evening (12 hourly), preferably after meals. Max. 2550 mg, i.e., 850 mg three times daily may be given or as directed by the physician.

Normally control of diabetes is obtained within a few days, but some time requires up to two weeks.

Contraindications:

Hepatic or renal impairment (withdraw if renal impairment suspected), predisposition to lactic acidosis, heart failure, severe infection or trauma, dehydration, alcohol dependence, pregnancy, breast feeding etc.

Precaution:

Because of possibility of hypoglycemia in combination therapy with a sulphonylurea or insulin, diabetic control should be monitored by blood sugar readings.

Side-effects:

Glucomet may cause gastro-intestinal adverse effects like diarrhoea, anorexia, nausea & vomiting. Lactic acidosis and malabsorption of vitamin B12 may be occurred. Patients may experience a metallic taste and there may be weight loss, which in some diabetics could be an advantage.

Drug Interaction:

It may enhance the effects of anti-coagulants. As such patients receiving the two drugs concomitantly may need adjustment of the anti-coagulant dosage.

Storage:

§         Store in a cool and dry place, protected from light.

§         Keep out of the reach of the children.

Packing:

Glucomet-500 Tablet: Box containing 10x10's tablets in blister pack.

Glucomet-850 Tablet: Box containing 5x10's tablets in blister pack.