Neobion

Vitamin B1, B6 & B12

Description:

Neobion is a combination of Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin). These vitamins play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. Neobion supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body's own repair mechanism and work in pain management.

Composition:

Each tablet contains:

Thiamine Hydrochloride (Vitamin B1) BP : 100 mg

Pyridoxine Hydrochloride (Vitamin B6) BP : 200 mg

Cyanocobalamin (Vitamin B12) BP : 200 mcg

Each 3 ml ampoule contains:

Thiamine Hydrochloride (Vitamin B1) BP : 100 mg

Pyridoxine Hydrochloride (Vitamin B6) BP : 100 mg

Cyanocobalamin (Vitamin B12) BP : 1000 mcg

Indication:

Chronic pains like sciatica, lumbago, trigeminal neuralgia, facial paralysis, optic neuritis as well as neuropathy & cardiac complications. Besides these, deficiency exists of relevant vitamins.

Dosage and administration:

Neobion Tablet: 1-2 tablets three times daily.

Neobion Injection: In severe cases, 1 ampoule daily until the acute symptoms subsides. For milder cases, & follow up therapy 2 or 3 should be injected weekly.

Side-effects:

Very rarely hypersensitive reaction and sensitivity disturbance may occur.

Use in pregnancy:

Neobion is safe for pregnant woman.

Use in lactating mother:

It is not known whether thiamine (Vitamin B1) is excreted in breast milk or not, but may be taken cautiously during lactation. Vitamin B6 & B12 have no adverse effect during lactation.

Children: Neobion may be given to children.

Precautions:

This combination (Vitamin B1+B6+B12) should be avoided in case of hypersensitivity to thiamine, cobalt or any other component of these ingredients. Cyanocobalamin should not be given before a diagnosis has been fully established because of the masking symptoms of subacute degeneration of the spinal cord.

Contraindication:

It should not be used in patients on levodopa therapy.

Drug Interactions:

Pyridoxine (Vitamin B6) reduces therapeutic effect of levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, chloramphenicol, aminosalisylic acid & histamine H2 receptor may reduce Vitamin B12 absorption.

Storage:

For Injection: Store below 25 c temperature.

For Tablet: Store in a cool and dry place, protected from light. Keep out of the reach of children.

Packaging:

Neobion Tablet: Each box contains 5x10's Neobion Tablets in blister pack.

Neobion Injection: Each box contains 2x5's Neobion Injection ampoules.