| OMNIFLOX
Sparfloxacin
Description:
Omniflox
is a synthetic, broad-spectrum antibacterial agent from the
difluoroquinolone family. It has been reported to be more active
in vitro than ciprofloxacin against some organisms, including
staphylococci and Mycobacteria, and has a much longer plasma
half-life (16 hours).
Composition:
Each film coated
Omniflox tablet contains Sparfloxacin INN 200 mg.
Indications:
Omniflox
is indicated for the treatment of following infections due to
susceptible micro-organisms:-
• Upper & lower
respiratory tract infections including sinusitis, acute exacerbation
of chronic bronchitis, community acquired and hospital acquired
pneumonia.
• Urinary tract
infections including gonococcal and non-gonococcal urethritis,
chancroid and other sexually transmitted diseases.
• Skin and soft
tissue infections.
• Prophylactic
use in different urological and ophthalmic operations.
Dosage &
administration:
The recommended
daily adult dose is two tablets (400 mg) on 1st day as a loading
dose, followed by one tablet (200 mg) daily as a maintenance
dose. Duration of maintenance treatment is 5 to 10 days. It
can be taken with or without food.
Children, pregnancy
& lactating mother:
Below 12 years
of children not recommended. Omniflox should be administered
in pregnant women & lactating mother only if the potential
maternal benefits justify the risks to the foetus/neonate.
Contraindications:
Hypersensitivity
to fluoroquinolones including sparfloxacin; growing children.
Precautions:
Renal disease,
gastric ulcers, concomitant use of NSAID's. avoid exposure UV
radiation during treatment. In renal failure of third degree
severity (creatinine clearance <30 ml/min) dosage modification
is recommended 400 mg on 1st day, 200 mg on 2nd & 3rd day
followed by 200 mg every 48 hours.
Adverse effects:
Side effects are
mild, transient and seldom. These are allergic reactions; photosensitization;
GIT (gastro-intestinal tract) disorders including nausea, vomiting,
diarrhoea; headache & sleep disturbance at the start of
treatment.
Drug Interactions:
Quinidine; sotalol;
erythromycin; astemizole; terfendine; vinca alkaloids.
Salts, oxides &
hydroxides of Mg, Al & Ca decrease the absorption of sparfloxacin.
Packing:
Box containing
1x10's tablets in Alu/Alu blister pack. |
