THIOBION

Thiamine

Description:

The active ingredient of Thiobion is a synthetic thiamine as hydrochloride, which has the same biological activity as natural vitamin B1. The thiamine requirement is directly correlated with the carbohydrate intake. As a rough guide, the requirement is 0.4 mg per 1000 calories. When the diet is rich in carbohydrates, the vitamin B1 intake should be adapted accordingly.

Composition:

Each tablet contains Thiamine hydrochloride BP 100 mg.

Indications:

Thiobion is specific in the treatment of the various manifestations of thiamine deficiency such as beriberi and Wernicke's encephalopathy, neuritis associated with pregnancy and pellagra. Supplementary Thiobion may be indicated prophylactically in conditions where there is low dietary intake or impaired gastrointestinal absorption of thiamine (e.g. alcohol) or where requirements are increased (Pregnancy, Carbohydrate-rich diet).

Dosage & administration:

Severe deficiency: 200-300 mg daily or as advised by the physician.

Precaution:

Mild allergic phenomena, such as sneezing or mild asthma are warning signs that further tablet may give rise to anaphylactic shock. To avoid this possibility it is advisable to start a second course of tablet with a second course of tablet with a dose considerably lower than that previously used.

Contraindications:

It is contraindicated in patients with known hypersensitivity to thiamine.

Side-effects:

Pruritus, urticaria, weakness, nausea, anorexia, angioneurotic oedema, cyanosis, pulmonary oedema, gastro-intestinal haemorrhage, etc. may occur. Anaphylactic reactions have occasionally been produced by tablet of thiamine given alone and sudden death has been reported, this risk of anaphylactic shock increases with repeated administration by the parenteral route.

Drug Interaction:

Administration with carbonates, citrates or barbiturates is not recommended.

Storage:

§         Store in a cool and dry place, protected from light.

§         Keep out of the reach of the children.

Packing:

Box containing 10x10's tablets in blister pack.