Arotrix-C lotion is the preparation of Permethrin 5% & Crotamiton 10% combination. Arotrix-C provides synergistic solutions for Scabies by ensuring complete eradication of Scabies and its associated symptoms.

Description

Arotrix-C lotion is the preparation of Permethrin 5% & Crotamiton 10% combination. Arotrix-C provides synergistic solutions for Scabies. Permethrin disrupts the sodium channels in mite nerves, thereby causes paralysis & death of mites; whereas Crotamiton inhibits TRPV4 calcium ion channels in sensory neurons, thereby reduces itching & inflammation. Thus, the combination ensures complete eradication of Scabies and its associated symptoms.

Presentation

    Arotrix-C Lotion: Each ml lotion contains Permethrin BP 50 mg and Crotamiton BP 100 mg with fragrance.

Indications

    Arotrix-C Lotion is indicated for the treatment of scabies and pruritus. Moreover, it is used for the relief of itching and skin irritation like sunburn, dry eczema, itchy dermatitis, allergic rashes, hives, nettle rash, chickenpox, insect bite and stings, heat rashes and personal itching.

Dosage & Administration

    Arotrix-C Lotion is suitable for adults, children of 2 months of age and above, and the elderly. It is for external use only and should not be applied to broken skin, mucous membranes or near the eyes. Arotrix-C Lotion should be applied to skin, which is clean, dry and cool. It should not be used immediately after a hot bath. Arotrix-C Lotion is intended for a single application over the whole body from the neck down to the soles of the feet, especially in body folds, after bathing when the skin is dry and clean. After 8-12 hours of application, the entire body should be thoroughly washed, and worn clothes and bed sheets should be washed with hot water. As a preventive measure, other family members should also use the lotion.

    Adults, Children over 2 years & Elderly: For children over 2 years & adults apply the lotion over the whole body but not the head and face. For the elderly patient apply the lotion over the whole body including the neck, face, ears and scalp. For all pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, external genitalia, breasts and buttocks. Avoid the area close to the eyes. Children under 2 years: Children under 2 years should only be treated under medical supervision. Apply the lotion over the whole body including the neck, face, ears and scalp. Pay particular attention to the areas between fingers and toes, under nails, wrists, armpits, palms of hands and soles of feet, external genitals and buttocks. Avoid the area around the mouth where the lotion could be licked off and the area around the eyes. Shake the bottle well before use.

Contrainidications

    Combination of Permethrin and Crotamiton is contra-indicated in patients with known hypersensitivity to permethrin or crotamiton.

Warning & Precautions

    Combination of Permethrin BP 5% and Crotamiton BP 10% lotion should be kept out of the reach of children. This lotion is for external use only. Nursing staff who routinely apply the lotion may wish to wear gloves to avoid any possible irritation to the hand. Avoid contact with the eyes. If the lotion comes into contact with the face or eyes, it should be rinsed off immediately with water. If excessive burning or irritation occurs, discontinue using and consult a physician if necessary.

Side effects

    Occasional reports of burning or stinging sensation which passes quickly. This is usually mild and occurs more frequently in patients with severe scabies. Transient signs and symptoms of skin irritation including rash or itching, erythema, oedema and eczema. These are generally considered to be part of the natural history of scabies.

Drug interaction

    The treatment of eczematous-like reactions with corticosteroids should be withheld prior to treatment with permethrin, as there is a risk of exacerbating the scabies infestation by reducing the immune response to the mite. The likelihood of interactions between the two treatments leading to potential adverse reactions or reduced efficacy is, however, small.

Use in special groups

    USE IN PREGNANCY & LACTATION: There is no experience to judge the safety of Permethrin & Crotamiton in pregnancy, therefore it is not recommended during pregnancy, especially in the first three months. It is not known whether the active substance passes into breast milk. Nursing mothers should avoid applying it around the nipples.

Packing

    Arotrix-C Lotion: Each bottle contains 60 ml lotion.